Allele Frequency Calculator

The Allele Frequency Calculator allows users to input population genetic data and calculates the frequencies of dominant and recessive alleles, as well as expected genotype frequencies, using Hardy-Weinberg equilibrium principles expressed as percentages.

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How to Use the Allele Frequency Calculator

The Allele Frequency Calculator is a tool designed to help you find the frequencies of dominant and recessive alleles in a given population. Here’s a step-by-step guide on how to use this calculator:

Step 1: Enter Total Population Size

  1. Locate the input field labeled Total Population Size.
  2. Enter the total number of individuals in the population using the provided input box.
  3. Ensure the number is at least 1, as required by the validation rules.

Step 2: Input Number of Dominant Homozygous (AA) Individuals

  1. Find the input labeled Number of Dominant Homozygous (AA).
  2. Enter the count of individuals that are homozygous dominant for the trait (AA).
  3. The number should be 0 or greater.

Step 3: Input Number of Heterozygous (Aa) Individuals

  1. Search for the input field labeled Number of Heterozygous (Aa).
  2. Type in the number of individuals that are heterozygous for the trait (Aa).
  3. Make sure the count is 0 or higher.

Step 4: Input Number of Recessive Homozygous (aa) Individuals

  1. Locate the field labeled Number of Recessive Homozygous (aa).
  2. Input the number of individuals that are homozygous recessive (aa).
  3. This value must also be 0 or above.

Step 5: Calculate the Allele Frequencies

Upon entering all required data, the calculator will compute:

  • Dominant Allele (A) Frequency (p): This frequency will be calculated based on the formula provided and displayed as a percentage with four decimal places.
  • Recessive Allele (a) Frequency (q): Similarly, this frequency will be shown as a percentage, reflecting the prevalence of the recessive allele.

Step 6: View Expected Genotype Frequencies

The calculator will also provide expected frequencies assuming Hardy-Weinberg equilibrium:

  • Expected AA Frequency (p²): The expected frequency for homozygous dominant individuals, calculated as the square of the dominant allele frequency.
  • Expected Aa Frequency (2pq): The expected frequency for heterozygous individuals, calculated using the formula 2pq.
  • Expected aa Frequency (q²): The expected frequency for homozygous recessive individuals, computed as the square of the recessive allele frequency.

Use this tool to efficiently determine and analyze the allele and genotype frequencies based on your population data.