This Carboplatin AUC Calculator helps users estimate the appropriate dose of carboplatin using parameters like weight, height, age, serum creatinine, gender, and target AUC to compute body surface area, creatinine clearance, and carboplatin dose based on the Calvert formula.
Carboplatin Auc Calculator
Use Our Carboplatin Auc Calculator
Step-by-Step Guide to Using the Carboplatin AUC Calculator
Step 1: Enter Weight
Begin by entering the patient’s weight in kilograms. This field is required, and the values must be between 20 kg and 300 kg. Ensure the accuracy of this data for precise calculations.
Step 2: Enter Height
Next, input the patient’s height in centimeters. Similar to the weight input, this field is mandatory. Acceptable values range from 100 cm to 250 cm. Accurate height is crucial for Body Surface Area (BSA) calculation.
Step 3: Enter Age
Provide the patient’s age in years. This is also a required field, with valid entries ranging from 18 years to 120 years.
Step 4: Enter Serum Creatinine Level
Input the serum creatinine level in mg/dL. This field must be filled, with acceptable values ranging from 0.1 mg/dL to 20 mg/dL. The serum creatinine level directly affects the calculation of the Glomerular Filtration Rate (GFR).
Step 5: Select Gender
Select the gender of the patient from the options: Male or Female. This selection impacts the Creatinine Clearance calculation, which varies slightly between genders.
Step 6: Enter Target AUC
Finally, enter the target AUC value. This is a required input, and it should be between 1 and 10. The target AUC helps determine the correct dosage of Carboplatin.
Results Interpretation
- Body Surface Area (BSA): The calculator uses the patient’s weight and height to compute the BSA employing the formula
0.007184 * height0.725 * weight0.425
. The result is provided in square meters (m²). - Creatinine Clearance: Calculated using age, weight, serum creatinine, and gender. The formula varies slightly between males and females and the result is expressed in mL/min.
- Glomerular Filtration Rate (GFR): Directly derived from the Creatinine Clearance, confirming kidney function.
- Carboplatin Dose: Utilizing the Calvert formula, it computes the required dose in mg, using the target AUC and GFR value.
Following the provided steps ensures accurate calculations of the desired Carboplatin dosage based on the specified patient parameters.